Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | GLA | P06280 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.69 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707005 | 1.00 | KDM4E (0.69) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| Hydrochloric Acid SCHEMBL2851355 | 0.99 | KDM4E (0.68) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| Hydrochloric Acid SCHEMBL1690850 | 0.99 | KDM4E (0.68) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| SCHEMBL3482463 | 0.87 | KCNH2 (0.56) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| SCHEMBL5612677 | 0.86 | KDM4E (0.67) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| SCHEMBL3482799 | 0.86 | KCNH2 (0.55) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| SCHEMBL26109570 | 0.85 | KDM4E (0.61) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| Water SCHEMBL28943973 | 0.84 | KDM4E (0.60) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| Sulfuric Acid SCHEMBL26103985 | 0.82 | KDM4E (0.57) | KDM4EHPGDALDH1A1GLAHSD17B10 | |
| Alfuzosin SCHEMBL34477 | 0.82 | KDM4E (1.00) | KDM4EHPGDALDH1A1GLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100183717-A1 | CONTROLLED-RELEASE FORMULATIONS | MUTUAL PHARMACEUTICAL COMPANY, INC., A PENNSYLVANIA CORPORATION | 2010-07-22 | — | — | US | disclosed |
| US-20100092556-A1 | ALFUZOSIN FORMULATIONS, METHODS OF MAKING, AND METHODS OF USE | MUTUAL PHARMACEUTICAL COMPANY, INC., A PENNSYLVANIA CORPORATION | 2010-04-15 | — | — | US | disclosed |
| US-20080160081-A1 | ALFUZOSIN FORMULATIONS, METHODS OF MAKING, AND METHODS OF USE | MUTUAL PHARMACEUTICAL COMPANY, INC. (US) | 2008-07-03 | — | — | US | disclosed |