SCHEMBL28474199

SCHEMBL28474199

[CH2]CCOc1ccc(O)c(C(C)=O)c1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 17/20 0.57
MAOA P21397 6/20 0.57
PPARD Q03181 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12428818 0.85 MAOB (0.58) MAOBMAOAPPARD
SCHEMBL1415014 0.85 MAOB (0.58) MAOBMAOAPPARD
SCHEMBL718653 0.84 MAOB (0.57) MAOBMAOAPPARD
SCHEMBL3652542 0.81 MAOB (0.61) MAOBMAOA
SCHEMBL25797602 0.81 MAOB (0.58) MAOBMAOAPPARD
SCHEMBL26331469 0.81 MAOB (0.58) MAOBMAOAPPARD
SCHEMBL8787008 0.81 MAOB (0.55) MAOBMAOAPPARD
SCHEMBL25797604 0.81 MAOB (0.55) MAOBMAOAPPARD
SCHEMBL9739884 0.79 MAOB (0.56) MAOBMAOA
SCHEMBL24474194 0.79 MAOB (0.58) MAOBMAOAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440068-A Cinnamate derivatives and their use as tyrosinase inhibitors and gels 陕西中医药大学 2020-07-24 CN claimed
CN-111440068-B Cinnamate derivative and application thereof as tyrosinase inhibitor and gel 陕西中医药大学 2023-08-11 CN disclosed
CN-111440068-A Cinnamate derivatives and their use as tyrosinase inhibitors and gels 陕西中医药大学 2020-07-24 CN disclosed