SCHEMBL28475392

SCHEMBL28475392

O=S(=O)(c1ccccc1N[C@H](CCN1CCOCC1)CSc1ccccc1)C(F)(F)F

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BCL2L1 Q07817 18/20 0.79
▸ BCL2 P10415 16/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28475394 1.00 BCL2L1 (0.79) BCL2L1BCL2
SCHEMBL25963424 0.90 BCL2L1 (0.78) BCL2L1BCL2
SCHEMBL20306172 0.90 BCL2L1 (0.78) BCL2L1BCL2
SCHEMBL554094 0.88 BCL2L1 (1.00) BCL2L1BCL2
SCHEMBL19263461 0.88 BCL2L1 (0.84) BCL2L1BCL2
SCHEMBL30777653 0.88 BCL2L1 (1.00) BCL2L1BCL2
SCHEMBL554095 0.88 BCL2L1 (1.00) BCL2L1BCL2
SCHEMBL25423836 0.85 BCL2L1 (0.94) BCL2L1BCL2
SCHEMBL10058370 0.85 BCL2L1 (0.74) BCL2L1BCL2
SCHEMBL25423839 0.85 BCL2L1 (0.94) BCL2L1BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626439-A2 METHODS OF TREATING ACUTE MYELOID LEUKEMIA The Regents of the University of Colorado, a body corporate (US) 2025-10-08 — — EP disclosed
WO-2024119090-A2 METHODS OF TREATING ACUTE MYELOID LEUKEMIA THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-06-06 — — WO disclosed
CN-111801320-A Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2020-10-20 — — CN disclosed
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