SCHEMBL28477386

SCHEMBL28477386

CCOC(=O)CS(=O)(=O)c1ccc(OCc2cccc(-c3c(C)cccc3C)c2)cc1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28476384 0.88 FFAR1 (1.00) FFAR1
SCHEMBL7411076 0.83 KMT2A (0.63) FFAR1
SCHEMBL28478788 0.80 FFAR1 (0.64) FFAR1
SCHEMBL15153627 0.80 FFAR1 (0.61) FFAR1
SCHEMBL28477798 0.80 FFAR1 (0.78) FFAR1
SCHEMBL15153539 0.79 FFAR1 (0.66) FFAR1
SCHEMBL15158921 0.77 FFAR1 (0.58) FFAR1
SCHEMBL28483355 0.77 FFAR1 (0.60) FFAR1
SCHEMBL15158918 0.77 FFAR1 (0.52) FFAR1
SCHEMBL12571007 0.77 FFAR1 (0.78) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108059607-B Sulfonylacetic acid or sulfonyl acetic acid derivative, and pharmaceutical composition, preparation method and application thereof 中国科学院上海药物研究所 2020-11-17 CN disclosed