Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SORD | Q00796 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478020 | 1.00 | GRM1 (0.44) | GRM1DPP4DPP8DPP9DPP7 | |
| SCHEMBL20064219 | 0.88 | GRM1 (0.44) | GRM1DPP4DPP8DPP9DPP7 | |
| SCHEMBL31357440 | 0.80 | GRM1 (0.44) | GRM1KDM4ESORDLMNAL3MBTL1 | |
| SCHEMBL13703142 | 0.80 | KDM4E (0.46) | GRM1KDM4ESORDLMNAL3MBTL1 | |
| SCHEMBL18239409 | 0.78 | KDM4E (0.49) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL23497906 | 0.78 | PIM1 (0.43) | GRM1DPP4DPP8DPP9DPP7 | |
| SCHEMBL23497613 | 0.78 | PIM1 (0.43) | GRM1DPP4DPP8DPP9DPP7 | |
| SCHEMBL1346067 | 0.77 | KDM4E (0.55) | KDM4ESORDLMNAL3MBTL1GPR119 | |
| Hydrochloric Acid SCHEMBL18228248 | 0.77 | KDM4E (0.48) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL12525383 | 0.76 | KDM4E (0.50) | GRM1KDM4ESORDLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793068-A | Heteroaryl compounds and uses thereof | 西建卡尔有限责任公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-105307657-B | Heteroaryl compounds and uses thereof | 西建卡尔有限责任公司 | 2020-07-10 | — | — | CN | disclosed |