Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473812 | 1.00 | TSHR (0.44) | TSHRNPSR1TRPM5DRD2DRD1 | |
| SCHEMBL28474805 | 1.00 | TSHR (0.44) | TSHRNPSR1TRPM5DRD2DRD1 | |
| SCHEMBL25373658 | 0.84 | TSHR (0.60) | TSHRNPSR1DRD2KDM4EHSD17B10 | |
| SCHEMBL30561807 | 0.84 | TSHR (0.60) | TSHRNPSR1DRD2KDM4EHSD17B10 | |
| SCHEMBL28471656 | 0.80 | TSHR (0.44) | TSHRNPSR1RORCCHRNB2CHRNA4 | |
| SCHEMBL28480427 | 0.80 | TSHR (0.44) | TSHRNPSR1TRPM5 | |
| SCHEMBL18939990 | 0.80 | TSHR (0.44) | TSHRNPSR1 | |
| SCHEMBL28471737 | 0.80 | TSHR (0.44) | TSHRNPSR1TRPM5 | |
| SCHEMBL28474809 | 0.80 | TSHR (0.44) | TSHRNPSR1 | |
| SCHEMBL28469436 | 0.80 | TSHR (0.44) | TSHRNPSR1TRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111718290-B | Synthesis method of multi-configuration isoindoline-1-carboxylic acid amino acid compound | 苏州爱玛特生物科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-111718290-A | Synthesis method of multi-configuration isoindoline-1-carboxylic acid amino acid compound | 苏州爱玛特生物科技有限公司 | 2020-09-29 | — | — | CN | disclosed |