Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17439622 | 0.92 | PDE4B (0.55) | PDE4BGRIN2BALOX5APFEN1 | |
| SCHEMBL17439580 | 0.90 | PDE4B (0.55) | PDE4BGRIN2BALOX5APFEN1HPGD | |
| SCHEMBL17439586 | 0.89 | PDE4B (0.55) | PDE4BGRIN2BALOX5APFEN1 | |
| SCHEMBL17447158 | 0.89 | PDE4B (0.57) | PDE4BGRIN2BALOX5APFEN1HPGD | |
| SCHEMBL17439511 | 0.89 | PDE4B (0.59) | PDE4BGRIN2BALOX5APFEN1 | |
| SCHEMBL17439521 | 0.86 | PDE4B (0.55) | PDE4BGRIN2BALOX5APFEN1 | |
| SCHEMBL17447181 | 0.86 | PDE4B (0.55) | PDE4BGRIN2BALOX5APFEN1 | |
| SCHEMBL17447167 | 0.86 | PDE4B (0.57) | PDE4BGRIN2BALOX5APFEN1 | |
| SCHEMBL17439537 | 0.85 | PDE4B (0.56) | PDE4BGRIN2BALOX5APFEN1 | |
| SCHEMBL17439532 | 0.85 | PDE4B (0.56) | PDE4BGRIN2BALOX5APFEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660996-B | 2, 5-substituted pyrimidines as PDE4 inhibitors | 格吕伦塔尔有限公司 | 2020-10-16 | — | — | CN | disclosed |