Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479203 | 1.00 | GRM4 (0.34) | GRM4 | |
| SCHEMBL28902454 | 0.84 | GRM4 (0.32) | GRM4 | |
| SCHEMBL28902455 | 0.84 | GRM4 (0.32) | GRM4 | |
| SCHEMBL30995686 | 0.84 | GRM4 (0.32) | GRM4 | |
| SCHEMBL28484978 | 0.78 | GAA (0.36) | GRM4 | |
| SCHEMBL28484975 | 0.78 | GAA (0.36) | GRM4 | |
| SCHEMBL28478061 | 0.75 | KDM4C (0.41) | GRM4 | |
| SCHEMBL28478058 | 0.75 | KDM4C (0.41) | GRM4 | |
| SCHEMBL20137432 | 0.72 | KDM4C (0.38) | GRM4 | |
| SCHEMBL28483551 | 0.72 | KDM4C (0.38) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107580598-B | Ethynyl derivatives as metabotropic glutamate receptor modulators | 豪夫迈·罗氏有限公司 | 2020-11-13 | — | — | CN | disclosed |