Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.55 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28474689 | 0.98 | CACNA2D1 (0.57) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL18125945 | 0.86 | CACNA2D1 (0.57) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL4882397 | 0.86 | CACNA2D1 (0.57) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL4882396 | 0.86 | CACNA2D1 (0.57) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL23182426 | 0.85 | CACNA2D1 (0.55) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL7782653 | 0.85 | CACNA2D1 (0.55) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL7787412 | 0.85 | CACNA2D1 (0.55) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL18508351 | 0.83 | CACNA2D1 (0.53) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL18508446 | 0.83 | CACNA2D1 (0.53) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL16114938 | 0.82 | CACNA2D1 (0.61) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111929370-B | Method for detecting related substances in pregabalin oral solution | 中国人民解放军军事科学院军事医学研究院 | 2022-07-01 | — | — | CN | claimed |
| CN-111929370-A | Method for detecting related substances in pregabalin oral solution | 中国人民解放军军事科学院军事医学研究院 | 2020-11-13 | — | — | CN | claimed |
| CN-111929370-B | Method for detecting related substances in pregabalin oral solution | 中国人民解放军军事科学院军事医学研究院 | 2022-07-01 | — | — | CN | disclosed |
| CN-111929370-A | Method for detecting related substances in pregabalin oral solution | 中国人民解放军军事科学院军事医学研究院 | 2020-11-13 | — | — | CN | disclosed |