SCHEMBL28480264

SCHEMBL28480264

C=CCOC(=O)c1c(C(=O)O)c(C(=O)O)c(C(=O)O)c(C(=O)O)c1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.52
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
SNCA P37840 1/20 0.40
RHOA P61586 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 2/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 2/20 0.36
TP53 P04637 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CACNA1B Q00975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30259412 1.00 CYP3A4 (0.52) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL10790238 1.00 CYP3A4 (0.52) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL27708808 0.94 CYP3A4 (0.47) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL28073815 0.94 CYP3A4 (0.47) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL7631407 0.91 CYP3A4 (0.59) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL22645741 0.91 CYP3A4 (0.44) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL28355430 0.84 CYP3A4 (0.46) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL1845640 0.84 CYP3A4 (0.46) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL8519916 0.84 CYP3A4 (0.46) CYP3A4TSHRALDH1A1HSD17B10SNCA
SCHEMBL11044588 0.83 CYP3A4 (0.44) CYP3A4TSHRALDH1A1HSD17B10SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111925479-B Modified polyacrylamide, preparation method thereof and polymer slurry 中铁四局集团有限公司 2022-02-08 CN claimed
CN-111925479-A Modified polyacrylamide, preparation method thereof and polymer slurry 中铁四局集团有限公司 2020-11-13 CN claimed
CN-111925479-B Modified polyacrylamide, preparation method thereof and polymer slurry 中铁四局集团有限公司 2022-02-08 CN disclosed
CN-111925479-B Modified polyacrylamide, preparation method thereof and polymer slurry 中铁四局集团有限公司 2022-02-08 CN disclosed
CN-111925479-A Modified polyacrylamide, preparation method thereof and polymer slurry 中铁四局集团有限公司 2020-11-13 CN disclosed
CN-111925479-A Modified polyacrylamide, preparation method thereof and polymer slurry 中铁四局集团有限公司 2020-11-13 CN disclosed