Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 19/20 | 0.71 |
| ▸ | RPS6KB1 | P23443 | 9/20 | 0.70 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28480350 | 1.00 | AKT1 (0.71) | AKT1RPS6KB1AURKA | |
| SCHEMBL28487122 | 0.91 | AKT1 (0.84) | AKT1RPS6KB1 | |
| SCHEMBL28487123 | 0.91 | AKT1 (0.84) | AKT1RPS6KB1 | |
| SCHEMBL15762711 | 0.91 | AKT1 (0.85) | AKT1RPS6KB1AURKA | |
| SCHEMBL22115907 | 0.91 | AKT1 (0.85) | AKT1RPS6KB1AURKA | |
| SCHEMBL28478997 | 0.87 | AKT1 (0.82) | AKT1RPS6KB1 | |
| SCHEMBL28478994 | 0.87 | AKT1 (0.82) | AKT1RPS6KB1 | |
| SCHEMBL20178091 | 0.83 | AKT1 (1.00) | AKT1RPS6KB1AURKA | |
| SCHEMBL15762453 | 0.83 | AKT1 (1.00) | AKT1RPS6KB1AURKA | |
| SCHEMBL28490662 | 0.83 | AKT1 (0.84) | AKT1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793254-B | Azaquinazoline carboxamide derivatives | 默克专利有限公司 | 2020-10-23 | — | — | CN | disclosed |