Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28480652 | 0.88 | AAK1 (0.52) | AAK1CYP3A4 | |
| SCHEMBL28479890 | 0.87 | AAK1 (0.70) | AAK1CYP3A4 | |
| SCHEMBL28479886 | 0.87 | AAK1 (0.70) | AAK1CYP3A4 | |
| SCHEMBL28487584 | 0.85 | AAK1 (0.72) | AAK1CYP3A4 | |
| SCHEMBL28480390 | 0.83 | AAK1 (0.67) | AAK1CYP3A4 | |
| SCHEMBL28484964 | 0.82 | AAK1 (0.61) | AAK1CYP3A4 | |
| SCHEMBL20574090 | 0.80 | AAK1 (0.68) | AAK1CYP3A4 | |
| SCHEMBL20574095 | 0.80 | AAK1 (0.68) | AAK1CYP3A4 | |
| SCHEMBL20446849 | 0.78 | AAK1 (0.85) | AAK1CYP3A4 | |
| SCHEMBL28485418 | 0.77 | AAK1 (0.63) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142655-A | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-108368084-B | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2020-10-16 | — | — | CN | disclosed |