Pyridine

Pyridine

SCHEMBL28482158

c1ccncc1.c1cnc(-c2ncccn2)nc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.60
NAPRT Q6XQN6 2/20 0.60
TSHR P16473 1/20 0.60
CYP2A6 P11509 2/20 0.46
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
P4HTM Q9NXG6 2/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CCR1 P32246 1/20 0.38
CCR5 P51681 1/20 0.38
CCR8 P51685 1/20 0.38
METAP1 P53582 1/20 0.38
BLM P54132 1/20 0.38
HIF1A Q16665 1/20 0.38
DOHH Q9BU89 1/20 0.38
TP53 P04637 1/20 0.38
NOTUM Q6P988 1/20 0.36
KMT2A Q03164 3/20 0.36
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL171853 0.82 HDAC8 (0.47) TDP1TSHRCYP2A6KDM4ELMNA
Pyridine SCHEMBL7904130 0.82
Pyridine SCHEMBL28889000 0.81 NAPRT (0.53) TDP1NAPRTTSHRCYP2A6NOTUM
Iodide SCHEMBL28731796 0.78 HDAC8 (0.44) TDP1TSHRCYP2A6KDM4ELMNA
Hydrochloric Acid SCHEMBL6535289 0.78 HDAC8 (0.44) TDP1TSHRCYP2A6KDM4ELMNA
SCHEMBL28383937 0.78 HDAC8 (0.44) TDP1TSHRCYP2A6KDM4ELMNA
Hydrochloric Acid SCHEMBL6534749 0.78 HDAC8 (0.44) TDP1TSHRCYP2A6KDM4ELMNA
Hydrochloric Acid SCHEMBL29713633 0.78 HDAC8 (0.44) TDP1TSHRCYP2A6KDM4ELMNA
SCHEMBL4270187 0.78 HDAC8 (0.44) TDP1TSHRCYP2A6KDM4ELMNA
SCHEMBL17144230 0.78 HDAC8 (0.44) TDP1TSHRCYP2A6KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108642857-B Bleaching working solution and application thereof 浙江理工大学 2020-10-30 CN claimed
CN-108948050-B Metal complex, preparation method thereof and bleaching working solution 浙江理工大学 2020-11-03 CN disclosed
CN-108642857-B Bleaching working solution and application thereof 浙江理工大学 2020-10-30 CN disclosed