Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848529 | 1.00 | TAAR1 (0.51) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL485589 | 0.78 | TAAR1 (0.56) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL13788689 | 0.78 | TAAR1 (0.56) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL1315541 | 0.78 | TAAR1 (0.56) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL26479172 | 0.78 | TAAR1 (0.56) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL485591 | 0.78 | TAAR1 (0.56) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL11941179 | 0.74 | TAAR1 (0.51) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL1314696 | 0.74 | TAAR1 (0.51) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL25239386 | 0.73 | TAAR1 (0.43) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL25239388 | 0.73 | TAAR1 (0.43) | TAAR1ALDH1A1SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472047-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-116472047-A | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |
| EP-2161277-A2 | Asymmetric synthesis of peptides | University of Reading (GB) | 2010-03-10 | — | — | EP | disclosed |