SCHEMBL28486576

SCHEMBL28486576

COC(=O)N(C1c2ccccc2-c2ccccc21)[C@@H](CCI)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
GPR3 P46089 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
SLC22A2 O15244 1/20 0.32
SLC22A3 O75751 1/20 0.32
CYP2D6 P10635 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892535 0.89 CYP1A2 (0.37) CYP1A2TSHRGPR3KMT2APOLB
SCHEMBL8893033 0.89 CYP1A2 (0.37) CYP1A2TSHRGPR3KMT2APOLB
SCHEMBL25177898 0.89 CYP1A2 (0.37) CYP1A2TSHRGPR3KMT2APOLB
SCHEMBL14648233 0.88 CYP1A2 (0.36) CYP1A2TSHRGPR3KMT2APOLB
SCHEMBL30510342 0.88 CYP1A2 (0.36) CYP1A2TSHRGPR3KMT2APOLB
SCHEMBL25178735 0.88 CYP1A2 (0.36) CYP1A2TSHRGPR3KMT2APOLB
SCHEMBL16933112 0.88 CYP1A2 (0.39) CYP1A2TSHRGPR3KMT2APOLB
SCHEMBL1000116 0.86 BCHE (0.37) CYP1A2TSHRKMT2APOLBMAPT
SCHEMBL25173040 0.86 PRSS1 (0.39) CYP1A2TSHRKMT2APOLBGAA
SCHEMBL20680418 0.86 SLC1A1 (0.35) CYP1A2TSHRGPR3KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111943870-A Synthesis method of L-2- (9H-fluorene-9-methoxycarbonylamino) -3-iodopropionic acid methyl ester 上海吉奉生物科技有限公司 2020-11-17 CN disclosed