Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906212 | 1.00 | PHGDH (0.30) | PHGDH | |
| SCHEMBL28987381 | 0.87 | ESR1 (0.36) | — | |
| SCHEMBL21428059 | 0.87 | ESR1 (0.36) | — | |
| SCHEMBL30294231 | 0.82 | NOTUM (0.35) | PHGDH | |
| SCHEMBL28898140 | 0.81 | — | — | |
| SCHEMBL21427882 | 0.77 | SLC10A1 (0.38) | — | |
| SCHEMBL22906211 | 0.77 | SLC10A1 (0.38) | — | |
| SCHEMBL21412861 | 0.70 | KMT2A (0.35) | PHGDH | |
| SCHEMBL21408326 | 0.70 | KMT2A (0.35) | PHGDH | |
| SCHEMBL21408328 | 0.70 | KMT2A (0.35) | PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974753-A | N-containing heterocyclic five-membered ring compound and application | 正大天晴药业集团股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115974754-A | N-containing heterocyclic five-membered ring compound and application | 正大天晴药业集团股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-111868026-A | Capsid protein assembly inhibitor containing N-heterocyclic five-membered ring, pharmaceutical composition and application thereof | 正大天晴药业集团股份有限公司 | 2020-10-30 | — | — | CN | disclosed |