Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482816 | 0.86 | CTPS1 (0.71) | CTPS1 | |
| SCHEMBL30528834 | 0.85 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL21373857 | 0.85 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL30528831 | 0.82 | CTPS1 (0.82) | CTPS1 | |
| SCHEMBL21373743 | 0.82 | CTPS1 (0.82) | CTPS1 | |
| SCHEMBL21373712 | 0.80 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL21373818 | 0.80 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL30528848 | 0.80 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL21373681 | 0.79 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL21373684 | 0.79 | CTPS1 (0.78) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868051-B | Aminopyrimidine derivatives as CTPS1 inhibitors | 斯泰普制药股份公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-111868051-A | Aminopyrimidine derivatives as CTPS1 inhibitors | 斯泰普制药股份公司 | 2020-10-30 | — | — | CN | disclosed |