Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697785 | 0.85 | MAPT (0.56) | MAPTALDH1A1PTGS2PTGS1KDM4E | |
| SCHEMBL12326165 | 0.85 | MAPT (0.56) | MAPTALDH1A1PTGS2PTGS1KDM4E | |
| SCHEMBL9869903 | 0.83 | PDE4A (0.57) | MAPTALDH1A1PTGS2KDM4EHPGD | |
| SCHEMBL3924409 | 0.76 | MAPT (0.57) | MAPTALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL6641490 | 0.74 | ESR2 (0.50) | MAPTALDH1A1PTGS2HPGDMEN1 | |
| Water SCHEMBL8845490 | 0.74 | MAPT (0.56) | MAPTALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL27582163 | 0.73 | PDE4A (0.52) | MAPTALDH1A1PTGS2KDM4EHPGD | |
| SCHEMBL17335722 | 0.73 | KDM1A (0.46) | ALDH1A1PTGS2HPGDPDE4AGAA | |
| SCHEMBL31401478 | 0.73 | MAPT (0.54) | MAPTALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL2494112 | 0.73 | MAPT (0.54) | MAPTALDH1A1KDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |