SCHEMBL28487533

SCHEMBL28487533

FCc1csc2ccc(Cl)cc12

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.69
KEAP1 Q14145 1/20 0.61
NFE2L2 Q16236 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.55
CA2 P00918 1/20 0.55
MAPT P10636 2/20 0.48
PKM P14618 1/20 0.43
EPHX1 P07099 1/20 0.43
GAB1 Q13480 1/20 0.42
UTS2R Q9UKP6 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4418009 0.83 CYP2A6 (0.71) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL156931 0.81 CYP2A6 (0.69) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL3180021 0.81 CYP2A6 (1.00) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL2089678 0.81 CYP2A6 (0.69) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL2094708 0.81 CYP2A6 (0.69) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL246112 0.81 CYP2A6 (0.69) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL2949120 0.81 CYP2A6 (0.69) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL31673840 0.81 CYP2A6 (1.00) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
Hydrochloric Acid SCHEMBL3575805 0.80 CYP2A6 (0.96) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2
SCHEMBL4324624 0.79 CYP2A6 (0.75) CYP2A6KEAP1NFE2L2SMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112062670-B Fluorination reagent and deoxidization fluorination method 三明市海斯福化工有限责任公司 2023-05-09 CN disclosed
CN-112062670-A Fluorination reagent and deoxidation fluorination method 三明市海斯福化工有限责任公司 2020-12-11 CN disclosed