SCHEMBL28488286

SCHEMBL28488286

CNc1cccc(-c2ccc(-c3cccc(NC)c3)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
MGLL Q99685 1/20 0.47
BRD4 O60885 1/20 0.46
KIF11 P52732 2/20 0.43
PNPLA2 Q96AD5 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
MAPT P10636 1/20 0.43
CNR1 P21554 2/20 0.43
CYP17A1 P05093 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
HSD17B1 P14061 2/20 0.42
HSD17B2 P37059 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
KMT2A Q03164 1/20 0.42
NTRK1 P04629 1/20 0.42
PLK1 P53350 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30288275 0.93 TSHR (0.59) TSHRMGLLBRD4HDAC6CNR1
SCHEMBL1038467 0.93 TSHR (0.59) TSHRMGLLBRD4HDAC6CNR1
SCHEMBL23576809 0.91 NPC1 (0.42) TSHRMGLLBRD4KIF11PNPLA2
SCHEMBL3788673 0.89 TAAR1 (0.52) TSHRMGLLBRD4KIF11PNPLA2
SCHEMBL13070601 0.89 CNR1 (0.57) CNR1
SCHEMBL16270804 0.89 CNR1 (0.50) TSHRMGLLBRD4KIF11MAPT
SCHEMBL16285571 0.88 MAPT (0.44) TSHRMGLLBRD4MAPTCYP17A1
SCHEMBL23577218 0.86 CNR1 (0.55) KIF11CNR1HSD17B2
SCHEMBL23576833 0.86 ABL1 (0.59) CYP3A4CYP2C9MEN1KMT2A
SCHEMBL18780196 0.86 HDAC6 (0.62) TSHRPNPLA2HDAC6MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111983908-A Belt, intermediate transfer belt, and image forming apparatus 富士施乐株式会社 2020-11-24 CN disclosed
CN-111913376-A Belt, intermediate transfer belt, and image forming apparatus 富士施乐株式会社 2020-11-10 CN disclosed