Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK1D | Q8IU85 | 15/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | MAP2K5 | Q13163 | 2/20 | 0.55 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.55 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.55 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.55 |
| ▸ | IDH2 | P48735 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | BLK | P51451 | 1/20 | 0.49 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488319 | 1.00 | CAMK1D (0.67) | CAMK1DKCNH2MAP2K5MAP3K11PIP5K1C | |
| SCHEMBL23113626 | 0.81 | CAMK1D (1.00) | CAMK1DKCNH2MAP2K5MAP3K11PIP5K1C | |
| SCHEMBL23113629 | 0.81 | CAMK1D (1.00) | CAMK1DKCNH2MAP2K5MAP3K11PIP5K1C | |
| SCHEMBL28496392 | 0.78 | CAMK1D (0.67) | CAMK1DKCNH2MAP2K5MAP3K11IDH2 | |
| SCHEMBL28492869 | 0.77 | CAMK1D (0.65) | CAMK1DROCK2 | |
| SCHEMBL28492864 | 0.77 | CAMK1D (0.65) | CAMK1DROCK2 | |
| SCHEMBL28493008 | 0.76 | CAMK1D (0.70) | CAMK1DROCK2 | |
| SCHEMBL28493012 | 0.76 | CAMK1D (0.70) | CAMK1DROCK2 | |
| SCHEMBL28499389 | 0.76 | CAMK1D (0.65) | CAMK1DKCNH2MAP2K5MAP3K11PIP5K1C | |
| SCHEMBL28499387 | 0.76 | CAMK1D (0.65) | CAMK1DKCNH2MAP2K5MAP3K11PIP5K1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119077-A | Kinase inhibitors | 曼彻斯特大学 | 2020-12-22 | — | — | CN | disclosed |