Furan

Furan

SCHEMBL28489697

ClCCOc1ccccc1.c1ccoc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 3/20 0.52
TAAR1 Q96RJ0 2/20 0.52
ALDH1A1 P00352 1/20 0.47
RECQL P46063 1/20 0.47
LTA4H P09960 2/20 0.46
PLA2G2A P14555 1/20 0.46
CHRNB2 P17787 2/20 0.43
CHRNB4 P30926 2/20 0.43
CHRNA3 P32297 2/20 0.43
CHRNA7 P36544 2/20 0.43
CHRNA4 P43681 2/20 0.43
HTR1B P28222 2/20 0.42
DRD2 P14416 2/20 0.42
DRD4 P21917 2/20 0.42
DRD3 P35462 2/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43271 0.87 KCNA3 (0.67) KCNA3TAAR1ALDH1A1RECQLLTA4H
Hydrochloric Acid SCHEMBL28255341 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLLTA4H
Water SCHEMBL11880867 0.85 KCNA3 (0.64) KCNA3TAAR1ALDH1A1RECQLLTA4H
Furan SCHEMBL28498789 0.82 TAAR1 (0.79) KCNA3TAAR1ALDH1A1RECQLLTA4H
Dimethylamine SCHEMBL8740809 0.79 HTR1B (0.61) KCNA3TAAR1ALDH1A1RECQLLTA4H
SCHEMBL1985916 0.79 KCNA3 (0.56) KCNA3TAAR1ALDH1A1RECQLLTA4H
Furan SCHEMBL28485181 0.78 TAAR1 (0.67) KCNA3TAAR1LTA4HPLA2G2A
SCHEMBL1544950 0.78 KCNA3 (0.75) KCNA3TAAR1ALDH1A1RECQLLTA4H
SCHEMBL28042242 0.78 KCNA3 (0.54) KCNA3TAAR1ALDH1A1RECQLLTA4H
Furan SCHEMBL28483614 0.77 TAAR1 (0.64) KCNA3TAAR1LTA4HPLA2G2AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107540647-B -amino alkyl furan phenol ether and preparation method and application thereof 湖南大学 2020-11-24 CN disclosed