Chrysin

Chrysin

SCHEMBL28492147

O=C(O)/C=C/c1ccccc1.O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12

nearest known ligand 0.74

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.74
▸ CYP3A4 P08684 8/20 0.74
▸ ABCB1 P08183 7/20 0.74
▸ MEN1 O00255 7/20 0.74
▸ KMT2A Q03164 7/20 0.74
▸ CYP2C9 P11712 6/20 0.74
▸ CYP2C19 P33261 6/20 0.74
▸ ALDH1A1 P00352 6/20 0.74
▸ POLH Q9Y253 5/20 0.74
▸ FTO Q9C0B1 5/20 0.74
▸ CYP1A1 P04798 5/20 0.74
▸ CYP1A2 P05177 5/20 0.74
▸ SMN1; SMN2 Q16637 5/20 0.74
▸ CYP1B1 Q16678 5/20 0.74
▸ TP53 P04637 5/20 0.74
▸ CYP2D6 P10635 5/20 0.74
▸ ABCG2 Q9UNQ0 4/20 0.74
▸ XDH P47989 4/20 0.74
▸ KDM4E B2RXH2 4/20 0.74
▸ HPGD P15428 4/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chrysin SCHEMBL29383577 0.86 MAPT (1.00) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL3453735 0.86 MAPT (1.00) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL44474 0.86 MAPT (1.00) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL27657189 0.85 MAPT (0.97) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL29183306 0.85 MAPT (0.97) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL29183315 0.85 MAPT (0.97) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL28150701 0.85 MAPT (0.97) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL28879361 0.85 MAPT (0.97) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL10809371 0.85 MAPT (0.97) MAPTCYP3A4ABCB1MEN1KMT2A
Chrysin SCHEMBL28107440 0.85 MAPT (0.97) MAPTCYP3A4ABCB1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111995605-B Chrysin cinnamate or its derivative and its preparation method 五邑大学 2023-02-17 — — CN claimed
CN-111995605-A Chrysin cinnamate or its derivative and its preparation method 五邑大学 2020-11-27 — — CN claimed
CN-111995605-B Chrysin cinnamate or its derivative and its preparation method 五邑大学 2023-02-17 — — CN disclosed
CN-111995605-B Chrysin cinnamate or its derivative and its preparation method 五邑大学 2023-02-17 — — CN disclosed
CN-111995605-B Chrysin cinnamate or its derivative and its preparation method 五邑大学 2023-02-17 — — CN disclosed
CN-111995605-A Chrysin cinnamate or its derivative and its preparation method 五邑大学 2020-11-27 — — CN disclosed
CN-111995605-A Chrysin cinnamate or its derivative and its preparation method 五邑大学 2020-11-27 — — CN disclosed
CN-111995605-A Chrysin cinnamate or its derivative and its preparation method 五邑大学 2020-11-27 — — CN disclosed
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