Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 6/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097145 | 1.00 | SLCO1B1 (0.55) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252713 | 0.90 | SLCO1B1 (0.61) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22436317 | 0.90 | SLCO1B1 (0.68) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22252656 | 0.86 | SLCO1B1 (0.60) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL23697664 | 0.84 | SLCO1B1 (0.55) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL29411847 | 0.84 | SLCO1B1 (0.55) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL19728880 | 0.84 | SLCO1B1 (0.55) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL29448522 | 0.84 | SLCO1B1 (0.55) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL21097119 | 0.84 | SLCO1B1 (0.57) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL28488384 | 0.84 | SLCO1B1 (0.57) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112055711-A | Cyclohexyl acid triazole azines as LPA antagonists | 百时美施贵宝公司 | 2020-12-08 | — | — | CN | disclosed |