Benzene

Benzene

SCHEMBL28495154

O=C(O)c1cc(C(=O)O)cc(-c2cc(C(=O)O)cc(C(=O)O)c2)c1.c1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 4/20 0.61
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
KMO O15229 1/20 0.52
TPMT P51580 3/20 0.50
TSHR P16473 3/20 0.50
TP53 P04637 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
CA3 P07451 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145349 0.97 DHODH (0.58) DHODHCA12CA1CA2CA7
SCHEMBL16271136 0.94 DHODH (0.56) DHODHCA12CA1CA2CA7
Hydrochloric Acid SCHEMBL28786184 0.94 DHODH (0.56) DHODHCA12CA1CA2CA7
Hydrochloric Acid SCHEMBL28650830 0.94 DHODH (0.56) DHODHCA12CA1CA2CA7
SCHEMBL12203147 0.94 DHODH (0.57) DHODHCA12CA1CA2CA7
SCHEMBL15521765 0.94 DHODH (0.57) DHODHCA12CA1CA2CA7
Water SCHEMBL28587831 0.94 DHODH (0.56) DHODHCA12CA1CA2CA7
Benzene SCHEMBL20211008 0.90 CA12 (0.61) DHODHCA12CA1CA2CA7
SCHEMBL1768904 0.89 DHODH (0.77) DHODHKMOTSHRDAONAPRT
SCHEMBL27736451 0.89 DHODH (0.77) DHODHKMOTSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909220-A Nickel (II) metal organic complex based on 3,3',5,5' -biphenyltetracarboxylic acid and preparation method and application thereof 河南省科学院化学研究所有限公司 2020-11-10 CN disclosed