Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19942887 | 1.00 | NR1H2 (0.38) | NR1H2ATMSRCMEN1ALDH1A1 | |
| SCHEMBL13577617 | 1.00 | NR1H2 (0.38) | NR1H2ATMSRCMEN1ALDH1A1 | |
| SCHEMBL30181011 | 1.00 | NR1H2 (0.38) | NR1H2ATMSRCMEN1ALDH1A1 | |
| SCHEMBL15273386 | 1.00 | NR1H2 (0.38) | NR1H2ATMSRCMEN1ALDH1A1 | |
| SCHEMBL376323 | 1.00 | NR1H2 (0.38) | NR1H2ATMSRCMEN1ALDH1A1 | |
| SCHEMBL29007753 | 0.93 | NR1H2 (0.41) | NR1H2ATMSRCCHRM2CHRM1 | |
| SCHEMBL10323879 | 0.90 | ATM (0.38) | NR1H2ATMMEN1ALDH1A1KMT2A | |
| SCHEMBL19942977 | 0.90 | ATM (0.34) | NR1H2ATMMEN1ALDH1A1MAPT | |
| SCHEMBL376609 | 0.90 | ATM (0.34) | NR1H2ATMMEN1ALDH1A1MAPT | |
| SCHEMBL13577619 | 0.90 | ATM (0.34) | NR1H2ATMMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793395-B | Fibroblast growth factor receptor inhibitors and uses thereof | 南京药捷安康生物科技有限公司 | 2021-01-05 | — | — | CN | disclosed |