Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 6/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28277451 | 0.85 | CA4 (0.38) | CA4ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL27941193 | 0.85 | CA4 (0.38) | CA4ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL28135098 | 0.84 | CA1 (0.38) | FAAHCA4 | |
| Trifluoroacetic Acid SCHEMBL65539 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL28322378 | 0.84 | CA4 (0.38) | CA4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7949096 | 0.81 | CA1 (0.53) | CA4 | |
| Trifluoroacetic Acid SCHEMBL358827 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL28839753 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL28342502 | 0.81 | CA4 (0.36) | CA4 | |
| Trifluoroacetic Acid SCHEMBL28078895 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094474-A | Preparation method of flexible high-conductivity elastomer composite material | 北京化工大学 | 2020-12-18 | — | — | CN | claimed |
| CN-118087250-A | Liquid metal composite porous elastic fiber and preparation method and application thereof | 之江实验室 | 2024-05-28 | — | — | CN | disclosed |
| CN-115181388-B | Stretchable electromagnetic shielding elastic material and preparation method thereof | 深圳先进电子材料国际创新研究院 | 2024-04-09 | — | — | CN | disclosed |
| CN-115532257-A | VOCs combustion catalyst used in sulfur-containing atmosphere and preparation method thereof | 太原理工大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-115181388-A | Stretchable electromagnetic shielding elastic material and preparation method thereof | 深圳先进电子材料国际创新研究院 | 2022-10-14 | — | — | CN | disclosed |
| CN-114232333-B | pAg-SiO 2 f one-dimensional porous composite material and preparation method and application thereof | 华南理工大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-112996262-B | Patterning method for enhancing wettability of liquid metal and polymer substrate | 华南理工大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114645459-A | Stretchable conductive antibacterial modified polyamide and preparation method thereof | 武汉工程大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-114232333-A | pAg-SiO2f one-dimensional porous composite material and preparation method and application thereof | 华南理工大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-112996262-A | Patterning method for enhancing wettability of liquid metal and high polymer substrate | 华南理工大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-112094474-A | Preparation method of flexible high-conductivity elastomer composite material | 北京化工大学 | 2020-12-18 | — | — | CN | disclosed |