Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL28500376 | 1.00 | FFAR4 (0.57) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Palmitic Acid SCHEMBL28574948 | 1.00 | FFAR4 (0.57) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| Erucic Acid SCHEMBL28018370 | 0.92 | PPARG (0.62) | FFAR4FFAR1ALDH1A1PPARGPPARD | |
| Stearic Acid SCHEMBL28504955 | 0.92 | PPARG (0.62) | FFAR4FFAR1ALDH1A1PPARGPPARD | |
| Erucic Acid SCHEMBL29013366 | 0.92 | PPARG (0.62) | FFAR4FFAR1ALDH1A1PPARGPPARD | |
| Erucic Acid SCHEMBL28018379 | 0.92 | PPARG (0.62) | FFAR4FFAR1ALDH1A1PPARGPPARD | |
| Palmitic Acid SCHEMBL28175506 | 0.92 | PPARG (0.62) | FFAR4FFAR1ALDH1A1PPARGPPARD | |
| SCHEMBL6901656 | 0.90 | SPHK1 (0.53) | FFAR1GPR84PPARDMAPT | |
| SCHEMBL6903713 | 0.90 | SPHK1 (0.53) | FFAR1GPR84PPARDMAPT | |
| Stearic Acid SCHEMBL28904022 | 0.81 | FFAR4 (0.62) | FFAR4FFAR1ALDH1A1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600759-A | Nonwoven web with visually distinguishable patterns and patterned surfactant | 宝洁公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116234525-A | Absorbent article with improved performance | 宝洁公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-114948441-A | Stretch laminate with beam elastics and shaped nonwoven layers | 宝洁公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-112218606-B | Stretch laminate with beam elastics and shaped nonwoven layers | 宝洁公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114025729-A | Absorbent article with functionally shaped topsheet and method of manufacture | 宝洁公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-113950312-A | Absorbent article with functionally shaped topsheet and method of manufacture | 宝洁公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-112218606-A | Stretch laminate with beam elastics and shaped nonwoven layers | 宝洁公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-107949476-B | Polyolefin-based elastic composition, method of making the same, and articles comprising the same | 陶氏环球技术有限责任公司 | 2020-12-18 | — | — | CN | disclosed |