Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28499453 | 1.00 | MAOB (0.44) | MAOBHRH3SCN9AMAOAHTR7 | |
| SCHEMBL28497246 | 0.91 | MAOB (0.48) | MAOBHRH3SCN9AMAOA | |
| SCHEMBL28497245 | 0.91 | MAOB (0.48) | MAOBHRH3SCN9AMAOA | |
| SCHEMBL28505288 | 0.90 | MAOB (0.48) | MAOBSCN9AMAOAALDH1A1 | |
| SCHEMBL28505287 | 0.90 | MAOB (0.48) | MAOBSCN9AMAOAALDH1A1 | |
| SCHEMBL28504429 | 0.88 | MAOB (0.42) | MAOBHRH3SCN9AMAOA | |
| SCHEMBL30705321 | 0.88 | MAOB (0.52) | MAOBSCN9AMAOA | |
| SCHEMBL28504424 | 0.88 | MAOB (0.42) | MAOBHRH3SCN9AMAOA | |
| SCHEMBL28505222 | 0.88 | MAOB (0.52) | MAOBSCN9AMAOA | |
| SCHEMBL28505223 | 0.88 | MAOB (0.52) | MAOBSCN9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041296-A | Aminoacetamides containing benzo-oxy-alicyclic structure and use thereof | 上海璃道医药科技有限公司 | 2020-12-04 | — | — | CN | claimed |
| CN-112041296-B | Aminoacetamides containing benzooxy alicyclic structures and uses thereof | 上海璃道医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-112041296-A | Aminoacetamides containing benzo-oxy-alicyclic structure and use thereof | 上海璃道医药科技有限公司 | 2020-12-04 | — | — | CN | disclosed |