Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16738701 | 0.94 | BRD4 (0.57) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL31073754 | 0.92 | BRD4 (0.55) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL16738745 | 0.89 | BRD4 (0.54) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL15069250 | 0.89 | BRD4 (0.57) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL28507931 | 0.88 | BRD4 (0.51) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL28501111 | 0.87 | BRD4 (0.49) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL16738065 | 0.86 | BRD4 (0.50) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL23403861 | 0.85 | BRD4 (0.57) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL16738938 | 0.85 | BRD4 (0.51) | BRD4TRIM24BRD2BRD3BRDT | |
| SCHEMBL16738749 | 0.85 | BRD4 (0.54) | BRD4TRIM24BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384784-B | Sulfonamide derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2021-01-12 | — | — | CN | disclosed |