Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | MYOC | Q99972 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.59 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | RAF1 | P04049 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460730 | 0.89 | CXCR2 (0.73) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL5594982 | 0.87 | CXCR2 (0.79) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL8103164 | 0.87 | MEN1 (0.69) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL8104826 | 0.87 | KMT2A (0.78) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL11027238 | 0.85 | MEN1 (0.88) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL4956157 | 0.84 | KMT2A (0.74) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL1305388 | 0.82 | TRPV1 (0.54) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL11832409 | 0.82 | MEN1 (0.88) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL30664565 | 0.82 | MEN1 (0.68) | KMT2AMEN1MAPTMAPK1NPC1 | |
| SCHEMBL21750900 | 0.82 | MEN1 (0.68) | KMT2AMEN1MAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530455-B | Urea substituted aromatic ring connecting dioxane and quinazoline compound or medicinal salt or hydrate and application as tyrosine kinase inhibitor | 北京赛特明强医药科技有限公司 | 2021-01-12 | — | — | CN | disclosed |