Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 3/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23872474 | 0.85 | KDM4E (0.48) | KDM4ESTAT3HIF1AKDM4CALPL | |
| SCHEMBL28496732 | 0.82 | GPR17 (0.45) | DYRK1AGPR17IDO1PRKAB2PRKAG1 | |
| SCHEMBL31647132 | 0.77 | KDM4E (0.46) | KDM4ESTAT3HIF1AKDM4CALPL | |
| SCHEMBL2862825 | 0.77 | KDM4E (0.59) | KDM4ESTAT3HIF1AKDM4CALPL | |
| SCHEMBL31725399 | 0.74 | KDM4E (0.52) | KDM4ESTAT3HIF1AKDM4CALPL | |
| SCHEMBL13132306 | 0.74 | MAP2K4 (0.43) | KDM4ESTAT3HIF1AALPLMAP2K4 | |
| SCHEMBL30258217 | 0.74 | KDM4E (0.63) | KDM4ESTAT3HIF1AMAP2K4DYRK1A | |
| SCHEMBL498163 | 0.74 | KDM4E (0.63) | KDM4ESTAT3HIF1AMAP2K4DYRK1A | |
| SCHEMBL2599805 | 0.72 | KDM4E (0.60) | KDM4ESTAT3HIF1AKDM4CLRRK2 | |
| SCHEMBL31162464 | 0.72 | PDPK1 (0.34) | MAPK1DYRK1AGPR17RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995577-A | Synthetic method of 4-fluoro indazole 3-carbonitrile or derivatives thereof | 上海代为化学科技有限公司 | 2020-11-27 | — | — | CN | disclosed |