SCHEMBL28501410

SCHEMBL28501410

COCC1(C(=O)O)CCN(C(=O)O)C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 2/20 0.40
PTGER4 P35408 1/20 0.40
PTGDR Q13258 1/20 0.40
USP2 O75604 4/20 0.34
CYP3A4 P08684 7/20 0.34
CYP2C19 P33261 5/20 0.34
HSD17B10 Q99714 3/20 0.34
CYP2D6 P10635 6/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
KDM1A O60341 1/20 0.33
ALDH1A1 P00352 5/20 0.33
CYP1A2 P05177 3/20 0.33
HIF1A Q16665 1/20 0.33
CYP2C9 P11712 2/20 0.32
MAPK1 P28482 2/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1119769 0.87 USP2 (0.36) PTGER2PTGER4PTGDRUSP2CYP3A4
SCHEMBL31231163 0.83 CYP4F2 (0.43) PTGER2PTGER4PTGDRUSP2CYP4F2
SCHEMBL3736290 0.83 CYP4F2 (0.43) PTGER2PTGER4PTGDRUSP2CYP4F2
Hydrochloric Acid SCHEMBL3788428 0.82 CYP4F2 (0.42) PTGER2PTGER4PTGDRUSP2CYP4F2
SCHEMBL30513223 0.81 CYP4F2 (0.36) PTGER2PTGER4PTGDRCYP4F2CYP4A11
SCHEMBL17009549 0.79 CYP2D6 (0.36) USP2CYP3A4CYP2C19HSD17B10CYP2D6
SCHEMBL3324938 0.78 CYP3A4 (0.37) USP2CYP3A4CYP2C19HSD17B10CYP2D6
SCHEMBL28250543 0.77 CYP4F2 (0.34) PTGER2PTGER4PTGDRCYP2C19CYP4F2
SCHEMBL16453921 0.77 CYP4F2 (0.34) PTGER2PTGER4PTGDRCYP4F2CYP4A11
SCHEMBL746366 0.77 CYP2C19 (0.31) PTGER2PTGER4PTGDRCYP2C19CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111592534-A Novel compounds 特殊治疗有限公司 2020-08-28 CN disclosed