SCHEMBL28501467

SCHEMBL28501467

CCCC[C]1C=Cc2ccccc21.Cl[Hf]Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SETD7 Q8WTS6 2/20 0.38
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
HTR1A P08908 4/20 0.33
DRD2 P14416 4/20 0.33
HTR2A P28223 4/20 0.33
SLC6A4 P31645 3/20 0.33
HRH1 P35367 3/20 0.33
HTR6 P50406 3/20 0.33
LMNA P02545 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
ALOX15 P16050 2/20 0.33
TP53 P04637 1/20 0.33
RET P07949 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
TSHR P16473 1/20 0.33
ADRA2C P18825 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219213 0.93 SETD7 (0.42) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL28573966 0.91 SETD7 (0.41) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL28818349 0.91 SETD7 (0.41) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL19643790 0.91 SETD7 (0.41) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL27948737 0.90 SETD7 (0.38) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL27933248 0.90 SETD7 (0.38) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL27948767 0.89 SETD7 (0.36) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL3685991 0.87 SETD7 (0.44) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL28807005 0.86 SETD7 (0.38) SETD7NR1H2NR1H3HTR1ADRD2
SCHEMBL28807003 0.86 SETD7 (0.38) SETD7NR1H2NR1H3HTR1ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218900-A Catalyst system comprising two hafnocene catalyst compounds 埃克森美孚化学专利公司 2021-01-12 CN claimed
CN-112218900-B Catalyst system comprising two hafnocene catalyst compounds 埃克森美孚化学专利公司 2023-07-04 CN disclosed
CN-112218900-A Catalyst system comprising two hafnocene catalyst compounds 埃克森美孚化学专利公司 2021-01-12 CN disclosed