Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519658 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL10380831 | 0.95 | TSHR (0.32) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4787287 | 0.77 | — | — | |
| Bromide SCHEMBL10457483 | 0.73 | — | — | |
| Bromide SCHEMBL6752530 | 0.73 | — | — | |
| Bromide SCHEMBL26969682 | 0.72 | — | — | |
| SCHEMBL275328 | 0.72 | TSHR (0.32) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4959977 | 0.70 | — | — | |
| Bromide SCHEMBL29011445 | 0.70 | TSHR (0.35) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27922143 | 0.69 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118562431-A | Rock shield glue and tile quick paving demolition-free construction method | 山东卓高新材料有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-109810679-B | Polyhydroxy oligomeric clay hydration inhibitor for deepwater drilling fluid and synthetic method thereof | 西安石油大学 | 2021-02-09 | — | — | CN | claimed |
| CN-109837073-B | Shale plugging inhibitor for drilling shale gas horizontal well and preparation method thereof | 西安石油大学 | 2021-01-19 | — | — | CN | claimed |
| CN-118562431-A | Rock shield glue and tile quick paving demolition-free construction method | 山东卓高新材料有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114181682-A | High-temperature-resistant salt-resistant cross-linked polymer filtrate reducer and preparation method and application thereof | 中海油田服务股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-109810679-B | Polyhydroxy oligomeric clay hydration inhibitor for deepwater drilling fluid and synthetic method thereof | 西安石油大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-109810679-B | Polyhydroxy oligomeric clay hydration inhibitor for deepwater drilling fluid and synthetic method thereof | 西安石油大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-109777379-B | Low-molecular-weight polymer shale inhibitor and preparation method thereof | 西安石油大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-109777379-B | Low-molecular-weight polymer shale inhibitor and preparation method thereof | 西安石油大学 | 2021-02-09 | — | — | CN | disclosed |
| CN-109837073-B | Shale plugging inhibitor for drilling shale gas horizontal well and preparation method thereof | 西安石油大学 | 2021-01-19 | — | — | CN | disclosed |
| CN-109837073-B | Shale plugging inhibitor for drilling shale gas horizontal well and preparation method thereof | 西安石油大学 | 2021-01-19 | — | — | CN | disclosed |
| CN-111793168-A | High-temperature-resistant salt-resistant filtrate reducer quadripolymer for drilling fluid | 安徽陆海石油助剂科技有限公司 | 2020-10-20 | — | — | CN | disclosed |