SCHEMBL28501596

SCHEMBL28501596

Cc1cc(C(=O)CC(C)C)ccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
ACE2 Q9BYF1 2/20 0.43
ALDH1A1 P00352 1/20 0.42
MYC P01106 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11044719 0.84 MEN1 (0.47) TDP1ALDH1A1
SCHEMBL988145 0.80 SMN1; SMN2 (0.48) ALDH1A1MYC
SCHEMBL26241553 0.79 CYP1A2 (0.49)
SCHEMBL11881710 0.79 MYC (0.56) TDP1ACE2ALDH1A1MYC
SCHEMBL16056966 0.79 GSK3B (0.55) ALDH1A1MYC
SCHEMBL11900206 0.77 TDP1 (0.53) TDP1ALDH1A1
SCHEMBL44342 0.77 MYC (0.58) TDP1ACE2ALDH1A1MYC
SCHEMBL29399874 0.77 MYC (0.58) TDP1ACE2ALDH1A1MYC
SCHEMBL25527620 0.76 SLC6A4 (0.51) ALDH1A1
SCHEMBL5797936 0.76 TDP1 (0.51) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111925299-A Continuous flow method for synthesizing 3-methyl-4-butyryl-5-nitrobenzoic acid methyl ester and reaction device thereof 浙江金立源药业有限公司 2020-11-13 CN disclosed