Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064896 | 0.90 | NPC1 (0.50) | TSHRHTTPOLBALOX15SMN1; SMN2 | |
| SCHEMBL504156 | 0.88 | TSHR (0.70) | TSHRHTTPOLBALOX15SMN1; SMN2 | |
| SCHEMBL9046507 | 0.81 | TSHR (0.65) | TSHRHTTPOLBALOX15LMNA | |
| SCHEMBL1420745 | 0.80 | HTT (0.78) | TSHRHTTPOLBALOX15SMN1; SMN2 | |
| SCHEMBL3826579 | 0.78 | NPC1 (0.78) | TSHRHTTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL6990203 | 0.78 | TSHR (0.66) | TSHRHTTPOLBALOX15HSD17B10 | |
| SCHEMBL1560918 | 0.78 | TSHR (0.66) | TSHRHTTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL8638411 | 0.77 | TPMT (0.66) | TSHRHTTPOLBALOX15HSD17B10 | |
| SCHEMBL9048230 | 0.77 | CA12 (0.62) | TSHRHTTPOLBALOX15SMN1; SMN2 | |
| SCHEMBL29633638 | 0.77 | TSHR (0.59) | TSHRHTTPOLBALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079741-A | Aminobenzoic acid derivative and preparation method and application thereof | 武汉化工新材料工业技术研究院有限责任公司 | 2020-12-15 | — | — | CN | disclosed |