Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771 | 0.76 | CYP2A6 (0.47) | CYP2A6PTK2KMT2A | |
| SCHEMBL28822926 | 0.75 | MAPK1 (0.33) | CYP2A6KMT2A | |
| SCHEMBL5110030 | 0.75 | AHR (0.48) | CYP2A6PTK2KMT2A | |
| SCHEMBL2155431 | 0.73 | CYP2A6 (0.52) | CYP2A6CYP11B2CYP11B1PTK2HDAC6 | |
| SCHEMBL5888962 | 0.72 | CYP2A6 (0.40) | CYP2A6CYP11B2CYP11B1PTK2KMT2A | |
| SCHEMBL27893679 | 0.71 | CYP2A6 (0.46) | CYP2A6CYP11B2CYP11B1PTK2KMT2A | |
| SCHEMBL28514778 | 0.71 | PDGFRB (0.34) | — | |
| SCHEMBL28906118 | 0.71 | — | — | |
| SCHEMBL28504316 | 0.70 | CYP11B1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL1135190 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112243374-A | SREBP inhibitors comprising a 6-membered central ring | 卡普勒斯疗法有限责任公司 | 2021-01-19 | — | — | CN | disclosed |