Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 10/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504603 | 1.00 | HTR2A (0.64) | HTR2AHTR2CMPOSLC6A4TSHR | |
| SCHEMBL28822903 | 1.00 | HTR2A (0.64) | HTR2AHTR2CMPOSLC6A4TSHR | |
| SCHEMBL29280790 | 0.85 | HTR2A (0.47) | HTR2AHTR2CSLC6A4TSHRMTNR1A | |
| SCHEMBL28905679 | 0.85 | HTR2A (0.64) | HTR2AHTR2CTSHRGPR84MTNR1A | |
| SCHEMBL28905678 | 0.85 | HTR2A (0.64) | HTR2AHTR2CTSHRGPR84MTNR1A | |
| SCHEMBL29280794 | 0.85 | HTR2A (0.47) | HTR2AHTR2CSLC6A4TSHRMTNR1A | |
| SCHEMBL28511287 | 0.84 | HTR2B (0.67) | HTR2AHTR2CMPOTSHRNOTUM | |
| SCHEMBL28511285 | 0.84 | HTR2B (0.67) | HTR2AHTR2CMPOTSHRNOTUM | |
| SCHEMBL23643112 | 0.83 | HTR2A (0.68) | HTR2AHTR2CMPOSLC6A4TSHR | |
| SCHEMBL28548649 | 0.82 | KDM4E (0.62) | HTR2AHTR2CMPOSLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041301-A | Compounds having iron death inducing activity and methods of use thereof | 费罗治疗公司 | 2020-12-04 | — | — | CN | disclosed |