Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262525 | 0.82 | KDM4E (0.50) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| SCHEMBL30505600 | 0.81 | KDM4E (1.00) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| SCHEMBL30381290 | 0.81 | KDM4E (1.00) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| SCHEMBL125654 | 0.81 | KDM4E (1.00) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| Fluoride SCHEMBL28821496 | 0.80 | KDM4E (0.96) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| Hydrochloric Acid SCHEMBL5266713 | 0.80 | KDM4E (0.96) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| SCHEMBL1088781 | 0.79 | KDM4E (0.67) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| Hydrochloric Acid SCHEMBL10553456 | 0.77 | KDM4E (0.64) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| Benzene SCHEMBL27872024 | 0.77 | KDM4E (0.70) | KDM4ELMNAKMT2AMEN1ALOX15 | |
| SCHEMBL3426743 | 0.77 | KDM4E (0.44) | KDM4ELMNAKMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321490-A | Auxiliary agent and preparation method thereof | 宿迁联盛科技股份有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-112321490-A | Auxiliary agent and preparation method thereof | 宿迁联盛科技股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-109952302-B | Positive allosteric modulators of muscarinic M1 receptors | 苏文生命科学有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-109952302-A | Muscarine M1 receptor forward direction allosteric modulators | 苏文生命科学有限公司 | 2019-06-28 | — | — | CN | disclosed |