Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907092 | 0.93 | MAOB (0.60) | MAOBNPC1CASP3RAB9ASENP8 | |
| SCHEMBL28515254 | 0.92 | MAOB (0.61) | MAOB | |
| SCHEMBL28509798 | 0.91 | MAOB (0.62) | MAOB | |
| SCHEMBL28506771 | 0.91 | MAOB (0.62) | MAOBMAOA | |
| SCHEMBL28521295 | 0.90 | MAOB (0.61) | MAOB | |
| SCHEMBL28906428 | 0.89 | MAOB (0.57) | MAOB | |
| SCHEMBL28519970 | 0.87 | MAOB (0.58) | MAOB | |
| SCHEMBL28509796 | 0.87 | MAOB (0.56) | MAOB | |
| SCHEMBL28515760 | 0.86 | MAOB (0.59) | MAOB | |
| SCHEMBL28528442 | 0.85 | HSD17B3 (0.50) | MAOBNPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761964-B | Coumarin-3-hydroxypyridine-4-one derivative, and preparation method and application thereof | 浙江工业大学 | 2021-02-02 | — | — | CN | disclosed |