Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | TPMT | P51580 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456900 | 1.00 | MEN1 (0.52) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL10012128 | 0.83 | MEN1 (0.68) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL31090352 | 0.77 | MEN1 (0.50) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL686591 | 0.77 | CA12 (0.61) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL9503850 | 0.77 | MEN1 (0.50) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL29914372 | 0.77 | CA12 (0.61) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL1403567 | 0.76 | MEN1 (0.82) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL13960184 | 0.75 | MEN1 (0.72) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL11677963 | 0.75 | TTR (0.60) | MEN1KMT2ATSHRALOX15HIF1A | |
| SCHEMBL21713201 | 0.74 | MEN1 (0.78) | MEN1KMT2ATSHRALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727605-B | Hydrogen bond organic framework material constructed based on condensed ring ligand, and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2020-12-29 | — | — | CN | claimed |