Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQLE | Q14534 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514145 | 1.00 | SQLE (0.50) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL28520038 | 0.86 | — | — | |
| SCHEMBL28506864 | 0.86 | — | — | |
| SCHEMBL28508970 | 0.81 | — | — | |
| SCHEMBL9844681 | 0.81 | — | — | |
| SCHEMBL28863722 | 0.78 | LSS (0.40) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL2627767 | 0.78 | SQLE (0.42) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL6738088 | 0.78 | — | — | |
| SCHEMBL11859933 | 0.77 | SQLE (0.53) | SQLEKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL11859938 | 0.77 | SQLE (0.53) | SQLEKMT2AMAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530241-B | Preparation method of benzo ring derivative with benzyl quaternary carbon center | 武汉大学 | 2021-02-02 | — | — | CN | claimed |
| CN-108530241-B | Preparation method of benzo ring derivative with benzyl quaternary carbon center | 武汉大学 | 2021-02-02 | — | — | CN | disclosed |