Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | GCG | P01275 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18642513 | 0.80 | GCG (0.48) | USP30CYP1A2CYP2A6GCGCHEK1 | |
| SCHEMBL28216268 | 0.80 | GCG (0.48) | USP30CYP1A2CYP2A6GCGCHEK1 | |
| SCHEMBL27102782 | 0.79 | ABL1 (0.46) | CYP1A2GCGABL1HCAR3KMT2A | |
| SCHEMBL13324075 | 0.79 | NPC1 (0.46) | CYP1A2MAPK10MAPK14POLBGAA | |
| SCHEMBL13804176 | 0.78 | CYP1A2 (0.54) | USP30CYP1A2CYP2A6CHEK1PDPK1 | |
| Hydrochloric Acid SCHEMBL7398907 | 0.76 | CYP1A2 (0.52) | USP30CYP1A2CYP2A6CHEK1PDPK1 | |
| SCHEMBL13101606 | 0.75 | ABL1 (0.57) | CHEK1ABL1NOTUMMTORGAA | |
| SCHEMBL12915410 | 0.74 | CYP1A2 (0.50) | USP30CYP1A2CYP2A6CHEK1PDPK1 | |
| SCHEMBL25242404 | 0.74 | PDPK1 (0.54) | USP30CYP1A2CYP2A6CHEK1PDPK1 | |
| SCHEMBL3662977 | 0.74 | CHEK1 (0.49) | CYP1A2CYP2A6CHEK1PDPK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105419-A | Fused ring compound | 豪夫迈·罗氏有限公司 | 2020-12-18 | — | — | CN | disclosed |