Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039897 | 1.00 | HDAC11 (0.45) | HDAC11USP2MEN1ALDH1A1POLB | |
| SCHEMBL30039180 | 1.00 | HDAC11 (0.45) | HDAC11USP2MEN1ALDH1A1POLB | |
| SCHEMBL21496820 | 0.91 | HDAC11 (0.49) | HDAC11C5AR1TIPARPHDAC6 | |
| SCHEMBL25932035 | 0.88 | HDAC11 (0.47) | HDAC11USP2MEN1ALDH1A1POLB | |
| SCHEMBL25932026 | 0.88 | HDAC11 (0.47) | HDAC11USP2MEN1ALDH1A1POLB | |
| SCHEMBL21496749 | 0.86 | HDAC11 (0.47) | HDAC11TIPARPSPRHDAC6 | |
| SCHEMBL28518722 | 0.86 | HDAC11 (0.47) | HDAC11TIPARPSPRHDAC6 | |
| SCHEMBL28521107 | 0.86 | HDAC11 (0.47) | HDAC11TIPARPSPRHDAC6 | |
| SCHEMBL21496744 | 0.84 | HDAC11 (0.61) | HDAC11TIPARPHDAC6 | |
| SCHEMBL21500463 | 0.84 | HDAC11 (0.61) | HDAC11TIPARPHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292370-A | Isoindolines as HDAC inhibitors | 瓦洛早期发现股份有限公司 | 2021-01-29 | — | — | CN | disclosed |