Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515763 | 0.89 | DDB1 (0.53) | DDB1CRBNIRAK4 | |
| SCHEMBL21071063 | 0.87 | DDB1 (0.43) | DDB1CRBNIRAK4EGFR | |
| SCHEMBL30169223 | 0.86 | DDB1 (0.53) | DDB1CRBNIRAK4 | |
| SCHEMBL22525464 | 0.86 | DDB1 (0.53) | DDB1CRBNIRAK4 | |
| SCHEMBL21071064 | 0.85 | DDB1 (0.43) | DDB1CRBNIRAK4EGFR | |
| SCHEMBL22526027 | 0.85 | DDB1 (0.52) | DDB1CRBNIRAK4EGFR | |
| SCHEMBL31578008 | 0.85 | DDB1 (0.41) | DDB1CRBNIRAK4EGFR | |
| SCHEMBL22525443 | 0.84 | DDB1 (0.51) | DDB1CRBNIRAK4EGFR | |
| SCHEMBL21996944 | 0.84 | DDB1 (0.51) | DDB1CRBNIRAK4EGFR | |
| SCHEMBL30169357 | 0.84 | DDB1 (0.51) | DDB1CRBNIRAK4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |