Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | SMO | Q99835 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190300 | 0.86 | TP53 (0.73) | ATMSMN1; SMN2GAAMAPK1MEN1 | |
| SCHEMBL30958899 | 0.84 | ATM (0.89) | ATMSMN1; SMN2GAAMAPK1MEN1 | |
| SCHEMBL16681578 | 0.84 | ATM (0.68) | ATMSMN1; SMN2KDM4EGAAMAPK1 | |
| Iodide SCHEMBL30758622 | 0.83 | ATM (0.86) | ATMSMN1; SMN2GAAMAPK1MEN1 | |
| SCHEMBL6349892 | 0.83 | ATM (0.68) | ATMSMN1; SMN2GAAMAPK1MEN1 | |
| SCHEMBL1918108 | 0.83 | NPC1 (0.81) | ATMSMN1; SMN2KDM4EGAAMEN1 | |
| SCHEMBL12191089 | 0.82 | SCN10A (0.69) | ATMSMN1; SMN2KDM4ESMOMAPT | |
| SCHEMBL16675161 | 0.81 | ABCB1 (0.68) | ATMSMN1; SMN2KDM4EGAAMAPK1 | |
| SCHEMBL16675167 | 0.81 | ABCB1 (0.68) | ATMSMN1; SMN2KDM4EGAAMAPK1 | |
| SCHEMBL12436011 | 0.81 | ATM (0.64) | ATMSMN1; SMN2KDM4EGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094228-A | Scutellarin aglycone derivative and preparation method thereof | 昆明龙津药业股份有限公司 | 2020-12-18 | — | — | CN | disclosed |