Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.80 |
| ▸ | KIT | P10721 | 4/20 | 0.73 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 1/20 | 0.68 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516830 | 0.97 | ABL1 (0.82) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL28516136 | 0.91 | ABL1 (0.87) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL22548931 | 0.89 | ABL1 (1.00) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL28515378 | 0.88 | ABL1 (0.82) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL22548932 | 0.87 | ABL1 (0.84) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL24626028 | 0.85 | ABL1 (0.79) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL29675159 | 0.85 | ABL1 (0.79) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL31620766 | 0.85 | KIT (1.00) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL29515093 | 0.84 | ABL1 (1.00) | ABL1KITFGFR1CYP2C9PDGFRA | |
| SCHEMBL3431360 | 0.84 | ABL1 (1.00) | ABL1KITFGFR1CYP2C9PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341378-A | Urea substituted alkynyl pyrimidine or urea substituted alkynyl pyridine compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2021-02-09 | — | — | CN | disclosed |