Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27003453 | 1.00 | CA1 (0.41) | CA1CA2CA12CA9HTT | |
| SCHEMBL3487568 | 1.00 | CA1 (0.41) | CA1CA2CA12CA9HTT | |
| SCHEMBL5116850 | 0.96 | HTT (0.44) | CA1CA2CA12CA9HTT | |
| SCHEMBL5120727 | 0.96 | HTT (0.44) | CA1CA2CA12CA9HTT | |
| SCHEMBL28944441 | 0.96 | CA1 (0.41) | CA1CA2CA12CA9HTT | |
| SCHEMBL28944439 | 0.96 | CA1 (0.41) | CA1CA2CA12CA9HTT | |
| SCHEMBL28779681 | 0.94 | HTT (0.47) | CA1CA2CA12CA9HTT | |
| SCHEMBL3487604 | 0.94 | HTT (0.47) | CA1CA2CA12CA9HTT | |
| SCHEMBL28779725 | 0.91 | HTT (0.47) | CA1CA2CA12CA9HTT | |
| SCHEMBL28779723 | 0.91 | HTT (0.47) | CA1CA2CA12CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-107108583-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2020-11-13 | — | — | CN | disclosed |