Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632367 | 1.00 | — | — | |
| SCHEMBL8856979 | 0.69 | TSHR (0.37) | TSHRCASP1ALDH1A1TRIM24TRIM33 | |
| SCHEMBL22491203 | 0.64 | — | — | |
| SCHEMBL20240821 | 0.64 | — | — | |
| SCHEMBL19955938 | 0.56 | TRIM24 (0.38) | TSHRCASP1ALDH1A1TRIM24TRIM33 | |
| SCHEMBL1425901 | 0.56 | — | — | |
| SCHEMBL111811 | 0.56 | — | — | |
| SCHEMBL22071458 | 0.56 | TRIM24 (0.38) | TSHRCASP1ALDH1A1TRIM24TRIM33 | |
| SCHEMBL1426217 | 0.56 | TRIM24 (0.38) | TSHRCASP1ALDH1A1TRIM24TRIM33 | |
| SCHEMBL19193626 | 0.56 | TRIM24 (0.38) | TSHRCASP1ALDH1A1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206872-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR8 agonists | 百济神州有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-112469722-A | Pyrazolo-triazolopyrimidine derivatives as A2A receptor antagonists | 百济神州有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-112437772-A | Bcl-2 inhibitors | 百济神州有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-112321590-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR8 agonists | 百济神州有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-110742893-A | Methods of treating cancer with A2A receptor antagonists | 百济神州(北京)生物科技有限公司 | 2020-02-04 | — | — | CN | disclosed |